Surface plasmon resonance spectroscopy
The platform accomodates a Biacore 2000 SPR system. For more information on how surface plasmon resonance (SPR) works, please visit the following SPR wikipedia web page:
AlphaLISA/AlphaScreen detection system
The Alphascreen technique allow to study the binding between two molecules in solution. For example, one binding partner is attach to bead A, whereas the second partner is attach to bead B. Light irradiation of the sample leads to the production of 1O2 by bead A. 1O2 diffuses and reacts with bead B if the beads are close enough together. This reaction leads to fluorescence emission by bead B, which is detected by the system.
Up to 384-well plates
Touch Screen: Easy to use; saves desktop space, can be used with gloves
Pre-coded assay protocols
Data export in Excel®/text formats to the network or into a USB memory stick
Easy access to the filter wheel with eight barcode identified filter
positions
Integrated data-analysis software: curve fit (lin-reg, spline, 4PL/5PL),
background subtraction, ratio calculation, IC50 calculation, Average, CV %, and Z –value
Windows® Vista® Operating System