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by Nathalie Ollivier - published on , updated on

Accelerating chemoselective peptide bond formation using bis(2-selenylethyl)amido peptide selenoester surrogates Laurent Raibaut, Marine Cargoët, Nathalie Ollivier, Yun Min Chang, Hervé Drobecq, Emmanuelle Boll, Rémi Desmet, Jean-Christophe M. Monbaliu and Oleg Melnyk, Chem. Sci. , 2016, 7, 2657-2665. DOI: 10.1039/C5SC03459K


Kinetically controlled chemoselective cyclization simplifies the access to cyclic and branched peptides Boll, E., Drobecq, H., Lissy, E., Cantrelle, F.-X., Melnyk, O. Org. Lett. 2016, 18, 3842-3845. DOI: 10.1021/acs.orglett.6b01847.


Cysteine 52 is the Achilles’ heel of SUMO-1 Drobecq, H. ; Boll, E. ; Sénéchal, M. ; Desmet, R. ; Saliou, J. M. ; Lacapère, J.-J. ; Mougel, A. ; Vicogne, V. ; Melnyk, O. Bioconjugate Chem. 2016, 27 1540–1546. DOI: 10.1021/acs.bioconjchem.6b00211


Insight into the SEA amide thioester equilibrium. Application to the synthesis of thioesters at neutral pH Pira, S. L., El Mahdi, O., Raibaut, L., Drobecq, H., Dheur, J., Boll, E., and Melnyk, O. Org. Biomol. Chem. 2016, 14, 7211-7216. DOI : 10.1039/C6OB01079B


Total chemical synthesis of SUMO proteins Melnyk, O.; Vicogne, J. Tetrahedron Letters 2016 , 57, 4319-4324. DOI: 10.1016/j.tetlet.2016.08.035